A New Haemoglobin Variant Haemoglobin J Birmingham a 120 (H3) Ala → Glu

Hb J- Meerut [α 120 (H3) Ala ->Glu (α1)] In A Turkish Male

Hb J Meerut is an infrequently found alpha-globin variant. It has previously been reported in various populations around the world. One particular case reported in 1994 included a Turkish family. In this report, details of a second case of Hb J Meerut in a Turkish male who is unrelated to the first family are described. In the present case a slight increase in the oxygen affinity of Hb J Meerut...

Haemoglobin J Tongariki (alpha-115 alanine--aspartic acid): the first new haemoglobin variant found in a Pacific (Melanesian) population.

In the course of a medico-genetic-anthropological investigation in I963 of the population of the island of Tongariki, in the Shepherd group of the New Hebrides, a haemoglobin variant was detected with a mobility which was greater than that of normal Hb on electrophoresis at alkaline pH, both by starch gel and by paper electrophoresis. The variant was found in this first survey in 17 of 228 pers...

New 13-Chain Variant of Haemoglobin A Found in Combination with Haemoglobin S

During a routine study of the parents of a 3month-old Jamaican child with the sickle-cell trait the father was found to have a haemoglobin electrophoretic pattern identical to that of homozygous sickle-cell disease. Because he was perfectly well and had no haematological abnormalities detailed studies of his haemoglobin constitution were undertaken. These indicate that he is heterozygous for bo...

Haemoglobin Osu - Christiansborg : A New - chain Variant of Haemoglobin A ( , 352 ( D 3 ) Aspartic Acid - - Asparagine ) in Combination with Haemoglobin S

A 63-year-old man, a member of the Ga tribe from the Osu-Christiansborg area in Accra was examined for hypertension. On incubation with 2% sodium metabisulphate his red cells readily sickle. Only two haemoglobin bands were demonstrated by paper electrophoresis at pH 8-9 (Cradock-Watson, Fenton, and Lehmann, 1959) and starch gel electrophoresis atpH 8-6 (Poulik, 1957), a minor one corresponding ...

Haemoglobin J in the French Canadian.